Scientists revive a powerful antibiotic that superbugs had defeated

Scientists have found a way to revive vancomycin, a powerful antibiotic that some dangerous bacteria have learned to resist. Instead of creating an entirely new drug, researchers paired vancomycin with a small molecule called pghi-4, which blocks a bacterial enzyme linked to resistance. The combination restored the antibiotic’s ability to kill drug-resistant E. faecium, raising hopes that similar chemical helpers could rescue other failing medicines.